A recent study by Global Market Insights Inc. projects that by 2030, the global market for serrata extract would be worth USD 200 million. The awareness of environmentally friendly Boswellia serrata production and the widespread adoption of such a method for better sustainability and traceability are identified in the research as the key driving forces behind the industry share. For instance, Verdure Sciences is expanding its sapling planting program to fulfill the rising demand for serrata extract while enhancing the quality of harvests. Overall, these acts have an impact on how well the resin is produced. Bioavailable products that are known to have anti-inflammatory characteristics and are used to treat joint pain will be produced by the environmentally friendly growth and harvesting of the Boswellia serrata plant.
Serrata extract is a herbal compound with therapeutic potential for asthma. Its main constituents are B. serrata gum resin and the Aegle marmelos fruit. This novel herbal composition, called LI13109F, has shown promise in improving IL-4 levels in a clinical study. It is currently under clinical investigation in patients with asthma.
What is Serrata Extract?
Boswellia serrata extract is a natural herbal product with anti-inflammatory properties. The resin is derived from the Boswellia tree and has long been used in folk medicine. The extract contains active boswellic acid, which inhibits pro-inflammatory enzymes. It has anti-inflammatory effects, and may help prevent cartilage loss. It may also reduce joint pain and stiffness.
The active ingredient in boswellia serrata extract is boswellic acid, which is a triterpene with anti-inflammatory properties. It has been found to inhibit several inflammatory processes, including tumor necrosis factor-alpha, IL-1beta, and NO. It has also been shown to inhibit mitogen-activated protein kinases (MAPKs) and nuclear factor-kappa B (NF-kappa B). The extract is also a natural antioxidant.
Boswellia serrata is an ancient herb used in Ayurveda. It has been used to treat brain edema, which is a common side effect of radiotherapy. Boswellia has also been used as a phytopharmaceutical for treating cancer and inflammation. Although studies are still underway, there have been preliminary results.
Boswellia serrata gum resin contains pentacyclic triterpenes, monoterpenes, and diterpenes. These compounds are effective against inflammation and are known to inhibit 5-lipoxygenase, leukocytes, and elastase. They also inhibit cancer cell proliferation and inhibit the activity of apoptosomerase.
A sustainability audit for Indian Boswellia serrata gum resin production techniques related to its use in a number of nutritional supplement applications will be carried out in February 2022 by innovative health & wellness science veteran PLT Health Solutions, Inc. and ethnobotanical consulting firm Botanical Liaisons, LLC. In order to establish sustainability, interviews with field workers, resin consolidators, ingredient manufacturers, and government officials were undertaken as part of the audit. Government assistance and similar corporate initiatives will increase the serrata extract market’s growth.
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Product’s capacity to reduce joint discomfort will help fuel demand for liquid serrata extract.
In the same way, cutting-edge health & wellness science pioneer PLT Health Solutions, Inc. and ethnobotanical consulting firm Botanical Liaisons, LLC joined forces to conduct a sustainability audit for Indian Boswellia serrata gum resin production techniques related to its use in a number of nutritional supplement applications in February 2022. As part of the audit to ascertain sustainability, interviews with field workers, resin consolidators, ingredient manufacturers, and government officials were undertaken. The size of the serrata extract market will increase as a result of these corporate initiatives and government funding.
The Benefits of Serrata Extract
Boswellic acid, a component of B. serrata, has a number of beneficial effects on the immune system. It has been shown to reduce the expression of several pro-inflammatory mediators, including TNFa and NF-kB. It also inhibits cyclooxygenase-2. This means that it could have therapeutic value in the treatment of lung diseases, including asthma.
Recent studies indicate that B. serrata’s anti-inflammatory effects are mediated by the elimination of senescent cells. These cells secrete pro-inflammatory mediators that are responsible for tissue dysfunction during obesity, aging, and inflammatory diseases. In mice, studies have shown that serrata extract and its active components, such as quercetin and kaempferol, have the ability to eliminate cellular senescence. In addition, these ingredients also promote peripheral nerve repair and Schwann cell proliferation.
Boswellia serrata is a plant native to India that has been used as a traditional remedy for centuries. Its resin contains boswellic acid, which is a group of three pentacyclic terpenes with anti-inflammatory properties. Boswellic acid is also rich in antimicrobial and antiproliferative properties.
Studies have shown that boswellic acid has anti-inflammatory activity and improves vascular remodeling. Furthermore, boswellic acid reduces enhanced oxidative stress and reduces inflammation through the TGFb1/Smad3 pathway. This ingredient has also shown beneficial effects on patients with arthritis and asthma.
During the projected period, a CAGR of over 11% is anticipated for the liquid sector. Serrata extract’s active ingredients, which are derived from tree resin, have anti-inflammatory, analgesic, and anti-arthritic properties. Serrata extract essential oil massaged into the afflicted joints on a regular basis together with the proper carrier oil eases pain and stiffness. Additionally, it has been demonstrated that the product controls the body’s immune response to reduce inflammation. The market expansion will be assisted by increased consumer knowledge of the health benefits of liquid-based serrata extract.
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increasing consumer interest for dietary supplements containing serrata extract in order to boost market profits
According to application, the market for serrata extract is expected to expand at a CAGR of more than 10.5% through 2030. The demand for dietary supplements containing serrata extract among the older population has grown due to the rise in incidence of joint disorders such osteoarthritis, rheumatoid arthritis, bursitis, and tendonitis. Between 2013 and 2015, about 58.5 million individuals in the United States received a yearly diagnosis of arthritis from their doctors, according to data from the Centers for Disease Control and Prevention. In addition, 78 million American adults are anticipated to suffer arthritis by the year 2040, according to estimates.
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Serrata extract has a number of medicinal properties. The boswellic acids it contains act as anti-inflammatory agents by inhibiting classical 5-lipoxygenase products. They also inhibit NF-B phosphorylation in response to inflammatory stimuli. Further, acetyl-11-keto-beta-boswellic acid inhibits testicular torsion injury in rats and inhibits the inflammatory pathways of caspase-3.
Boswellic acids inhibit the synthesis of inflammatory mediators and counteract free radicals in the body. They also inhibit the activity of hyaluronidase. In fact, serrata has demonstrated antibacterial, anti-inflammatory, and antiviral activity. These effects are important for further research and the development of more effective delivery systems.
Recent studies on boswellia serrata extract have confirmed that it has a high safety margin. In mice and Wistar rats, oral administration of the extract did not result in mortality or signs of toxicity. Additionally, administration of the extract for 28 days showed no significant changes in liver and renal function, nor did it induce any behavioral changes.
Boswellic acid inhibits pro-inflammatory mediators in the lung. It inhibits NF-kB and TNFa, two molecules responsible for tissue dysfunction in inflammatory diseases. Boswellic acid also reduced the number of IL-17A-producing CD8+ T cells and bioactive 5-LOX lipid mediators.